Biotechnology company focused on developing cancer treatments.
Exelixis, Inc. is a prominent biotechnology company focused exclusively on advancing oncology treatments within the United States. Specializing in the discovery, development, and commercialization of innovative medicines, Exelixis is renowned for its groundbreaking therapies aimed at addressing various forms of cancer. The company's flagship products include CABOMETYX tablets, prescribed for patients with advanced renal cell carcinoma following prior anti-angiogenic therapy, and COMETRIQ capsules, designed for progressive and metastatic medullary thyroid cancer treatment. Both medications are derived from cabozantinib, a potent inhibitor of multiple tyrosine kinases crucial in cancer progression, such as MET, AXL, RET, and VEGF receptors.
Additionally, Exelixis offers COTELLIC, a MEK inhibitor used in combination therapies for advanced melanoma, and MINNEBRO, a selective blocker of the mineralocorticoid receptor primarily for hypertension treatment in Japan. The company continues to expand its pipeline with promising candidates like zanzalintinib, an oral tyrosine kinase inhibitor targeting VEGF receptors, MET, AXL, and MER, among others. Other devellopments include XB002, an antibody-drug conjugate targeting tissue factor for solid tumors, XL102, a CDK7 inhibitor for advanced solid tumors, and XB002 for non-hodgkin's lymphoma.
Established in 1994 as Exelixis Pharmaceuticals, Inc., the company underwent a name change to Exelixis, Inc. in February 2000. Headquartered in Alameda, California, Exelixis maintains strategic research collaborations and licensing agreements with global pharmaceutical leaders such as Ipsen Pharma SAS, Takeda Pharmaceutical Company Ltd., and F. Hoffmann-La Roche Ltd. These partnerships facilitate the development and commercialization of its innovative treatments, underscoring Exelixis' commitment to advancing cancer care through cutting-edge biotechnological advancements.
Exelixis, Inc. stands at the forefront of the biotechnology industry, dedicated to transforming cancer treatment paradigms with its robust portfolio of therapies and ongoing research initiatives. The company's strategic alliances and expansive network of collaborations position it as a pivotal player in the global fight against cancer, driving innovation and improving outcomes for patients worldwide.