Develops therapies for autoinflammatory and autoimmune diseases, focusing on addressing inflammation-driven diseases with novel biologic treatments.
Kiniksa Pharmaceuticals, Ltd. is a biopharmaceutical company dedicated to identifying, acquiring, developing, and commercializing therapeutic medications tailored for patients worldwide grappling with severe and unmet medical needs.
At the forefront of its portfolio are several promising product candidates. ARCALYST stands out as an interleukin-1alpha and interleukin-1beta inhibitor intended for treating recurrent pericarditis, a condition characterized by inflammation affecting the cardiovascular system. Additionally, Mavrilimumab, a monoclonal antibody inhibitor, has completed Phase II clinical trials for giant cell arteritis, while Vixarelimab, another monoclonal antibody, is undergoing Phase 2a clinical trials for prurigo nodularis, a chronic inflammatory skin disorder. Kiniksa is also advancing KPL-404, a monoclonal antibody designed to inhibit the CD40-CD154 interaction crucial for B-cell maturation, immunoglobulin class switching, and type 1 immune responses.
Established in 2015 and headquartered in Hamilton, Bermuda, Kiniksa Pharmaceuticals operates with a mission to address critical medical challenges through innovative therapeutic solutions. The company's robust pipeline underscores its commitment to advancing treatments that improve patient outcomes and quality of life globally.
By leveraging cutting-edge research and development strategies, along with strategic partnerships, Kiniksa Pharmaceuticals continues to expand its capabilities in biopharmaceutical innovation, aiming to make a significant impact in healthcare sectors worldwide.