Develops therapies for autoimmune diseases and inflammation using its proprietary T cell modulation technology.
Connect Biopharma Holdings Limited is a dynamic clinical-stage biopharmaceutical company specializing in the research and development of innovative immune modulators aimed at treating severe autoimmune diseases and inflammation. At the forefront of its pipeline is CBP-201, an anti-interleukin-4 receptor alpha antibody currently undergoing Phase IIb clinical trials. This promising candidate targets inflammatory allergic conditions such as atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyps, addressing significant unmet medical needs.
In addition to CBP-201, Connect Biopharma is advancing several other compelling products. CBP-307, a small molecule modulator targeting sphingosine 1-phosphate receptor 1, is in Phase II trials for autoimmune-related inflammatory diseases. The company also pioneers CBP-174, a small molecule histamine receptor 3 antagonist designed for oral administration to alleviate chronic itch associated with skin inflammation. Further expanding its portfolio, CBP-233, a humanized antibody against interleukin-33, is in the preclinical stage, targeting T helper 2 inflammation.
Founded in 2012 and headquartered in Taicang, China, Connect Biopharma exemplifies a commitment to innovation and scientific excellence in the field of biopharmaceuticals. With a robust pipeline and strategic focus on transformative therapies, the company aims to redefine treatment paradigms and improve outcomes for patients worldwide suffering from debilitating autoimmune conditions.