Safeguard Scientifics, Inc. (SFE)

Diversified holding company that provides capital and operational support to technology-driven businesses in the healthcare and technology sectors.

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Safeguard Scientifics, Inc., based in Radnor, Pennsylvania, has transitioned away from active investing and now operates primarily as a private equity and venture capital firm. Specializing in a wide array of financial strategies including expansion financings, growth capital, management buyouts, and industry consolidations, Safeguard Scientifics initially focuses on Series A-C rounds and occasionally engages in seed round investments. The firm directs its investments towards companies within the technology, financial services, and healthcare sectors.

In the technology sector, Safeguard Scientifics targets companies involved in software as a service, digital media, cybersecurity, predictive analytics, artificial intelligence, and various other tech-enabled services. Within the healthcare domain, its interests extend to molecular diagnostics, medical devices, digital health solutions, and specialty pharmaceuticals. Operating primarily in the United States, with a strategic focus on the Mid-Atlantic region and Southeastern Canada, Safeguard Scientifics typically commits between $5 million to $25 million in growth equity and between $5 million to $10 million in early-stage financing.

Founded in 1953 as Lancaster Corporation and later rebranded as Safeguard Scientifics, Inc. in 1981, the company has maintained a steadfast commitment to fostering growth and innovation. It prefers to assume significant ownership stakes in its portfolio companies, ranging from 20% to 50%, and actively engages by taking board seats to influence strategic direction. Although its focus has shifted away from new investments, Safeguard Scientifics continues to leverage its extensive expertise and network to support the ongoing development of its existing portfolio.

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