Biotechnology company focused on discovering, developing, and commercializing novel small molecule drugs for immune and hematologic disorders.
Rigel Pharmaceuticals, Inc. is a pioneering biotechnology company dedicated to the discovery, development, and provision of small molecule drugs aimed at improving the lives of patients affected by hematologic disorders, cancer, and rare immune diseases. Founded in 1996 and headquartered in South San Francisco, California, the company focuses on advancing innovative therapies that address significant medical challenges.
Among its portfolio, Rigel Pharmaceuticals has successfully commercialized Tavalisse, an oral spleen tyrosine kinase inhibitor designed for adult patients diagnosed with chronic immune thrombocytopenia. Additionally, the company offers Rezlidhia, a non-intensive monotherapy tailored for adult patients with relapsed or refractory acute myeloid leukemia (AML) carrying a susceptible isocitrate dehydrogenase-1 (IDH1) mutation, as confirmed by an FDA-approved test.
Rigel Pharmaceuticals is also actively developing Fostamatinib, which has completed Phase III clinical trials for treating warm autoimmune hemolytic anemia and has shown promise in the treatment of COVID-19. The company's ongoing Phase III trials for Fostamatinib aim to evaluate its efficacy in hospitalized patients with COVID-19, underscoring its commitment to addressing critical medical needs during global health challenges.
Furthermore, Rigel Pharmaceuticals collaborates with esteemed partners such as Eli Lilly and Company, BerGenBio ASA, and Daiichi Sankyo to advance its diverse clinical programs. These collaborations include developing interleukin receptor-associated kinase inhibitors and receptor-interacting serine/threonine-protein kinase inhibitors, highlighting the company's collaborative approach to accelerating therapeutic innovation. With a steadfast focus on scientific excellence and patient-centric innovation, Rigel Pharmaceuticals continues to push the boundaries of biotechnology to deliver impactful treatments worldwide.