Clinical-stage biopharmaceutical company developing targeted small molecule therapies for oncology.
PMV Pharmaceuticals, Inc. is a leading precision oncology company dedicated to advancing the field through its focus on discovering and developing small molecule therapies designed to target p53 mutations in cancer. Based in Cranbury, New Jersey, PMV Pharmaceuticals specializes in developing tumor-agnostic treatments that address specific mutations of the p53 protein.
At the forefront of PMV Pharmaceuticals' innovative pipeline is PC14586, its flagship small molecule candidate. PC14586 is engineered to correct the Y220C mutation found in the p53 protein, thereby restoring its wild-type function. The company's research extends beyond this initial candidate to include various programs targeting other critical p53 mutations such as Wild-type p53 Induced-Phosphatase, R282W, and R273H, among others.
Founded originally as PJ Pharmaceuticals, Inc. and rebranded in July 2013, PMV Pharmaceuticals leverages a robust foundation of scientific expertise and strategic partnerships to propel its pioneering research. The company's commitment to precision oncology and its pursuit of novel therapeutic solutions highlight its dedication to addressing the complexities of cancer treatment.
Since its inception in 2013, PMV Pharmaceuticals has positioned itself as a pivotal player in the biopharmaceutical industry. With a steadfast focus on leveraging cutting-edge science to develop transformative therapies, PMV Pharmaceuticals continues to advance its mission to improve outcomes for patients affected by p53-mutated cancers.