Clinical-stage gene therapy company developing treatments for inherited and acquired diseases.
MeiraGTx Holdings plc is a clinical stage gene therapy company dedicated to advancing treatments for patients confronting severe diseases. The company specializes in developing therapies for a range of medical conditions, prominently focusing on ocular diseases causing inherited blindness and Xerostomia resulting from radiation treatment for head and neck cancers. Additionally, MeiraGTx is actively pursuing treatments for degenerative diseases, neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and Parkinson's disease.
At the forefront of its clinical development efforts are several Phase 1/2 programs targeting Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia. These initiatives underscore the company's commitment to addressing significant unmet needs in vision-related disorders and radiation-induced complications. MeiraGTx is also poised to launch clinical studies focused on xerostomia associated with Sjogren's syndrome, further broadening its therapeutic portfolio.
In addition to its clinical pursuits, MeiraGTx is actively engaged in preclinical programs aimed at advancing treatments for various neurodegenerative diseases. The company's collaborative efforts include a research partnership with Janssen Pharmaceuticals, Inc., aimed at developing regulatable gene therapy utilizing MeiraGTx's proprietary riboswitch technology.
Founded in 2015 and headquartered in New York, New York, MeiraGTx Holdings plc continues to drive innovation in gene therapy, leveraging its expertise to pioneer transformative treatments that improve the lives of patients facing complex and challenging medical conditions.