Develops therapies for ear, nose, and throat disorders, focusing on localized drug delivery to treat chronic rhinosinusitis.
Lyra Therapeutics, Inc. operates as a clinical-stage company specializing in the development and commercialization of innovative drug and delivery solutions tailored for localized treatment of ear, nose, and throat diseases. Central to its approach is the XTreo technology platform, engineered to administer medications directly to affected tissues with sustained efficacy from a single dose. Among its leading product candidates is LYR-210, an implantable anti-inflammatory drug matrix currently undergoing Phase II clinical trials for chronic rhinosinusitis (CRS). Additionally, LYR-220 targets CRS patients, both with and without nasal polyps.
Founded in 2005 and headquartered in Watertown, Massachusetts, Lyra Therapeutics, Inc. was originally established as 480 Biomedical, Inc. before rebranding in July 2018. The company's evolution underscores its long-standing commitment to pioneering solutions that enhance treatment outcomes and patient care in otolaryngology. With a strong emphasis on scientific innovation and clinical development, Lyra Therapeutics continues to advance its pipeline of therapeutic options aimed at addressing unmet medical needs within the ENT community.
Driven by a vision to transform localized therapies, Lyra Therapeutics, Inc. remains at the forefront of biomedical research and development. Through strategic partnerships and ongoing clinical advancements, the company strives to deliver breakthrough treatments that improve quality of life for patients suffering from chronic ENT conditions worldwide.