Develops innovative therapies for rare diseases using its proprietary Resokine protein platform.
aTyr Pharma, Inc., a pioneering biotherapeutics company headquartered in San Diego, California, specializes in the discovery and development of innovative medicines targeting novel immunological pathways. At the forefront of its research is efzofitimod, the company's lead therapeutic candidate currently undergoing Phase III clinical trials for pulmonary sarcoidosis. Additionally, efzofitimod is being evaluated in Phase 1b/2a trials for the treatment of various interstitial lung diseases (ILDs) including chronic hypersensitivity pneumonitis and connective tissue disease related ILD.
In addition to efzofitimod, aTyr Pharma is advancing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase, in preclinical development aimed at treating fibrosis. The company's pipeline also includes ATYR0750, a domain of alanyl-tRNA synthetase under development for liver disorders. These innovative approaches underscore aTyr Pharma's commitment to addressing complex diseases through targeted therapeutic interventions.
Established in 2005, aTyr Pharma has forged strategic collaborations such as its partnership with Kyorin Pharmaceutical Co., Ltd., focusing on the development and commercialization of efzofitimod for ILDs in Japan. With a strong foundation in scientific research and a dedication to advancing patient care, aTyr Pharma continues to expand its capabilities and pursue novel treatments that have the potential to make a significant impact on global healthcare.